NoelDP said:
Have you tried posting in the programs' own forums?
They are much more likely to have relevant experience than we are.

Really, we can only be reasonably certain to fix problems with Windows - or if one of our members is lucky(?) enough to have met the same problem.

Have you reinstalled OTTER following the instructions here?
Unemployment Insurance Tax OTTER HOME PAGE

I can't help with the GIS program, as GIS is too generic a term - for any hope of some help, more details would be required (developer, etc)
I would like to note that I am having the same error dialog ("File name or class name not found during Automation operation") with a different program, which just so happens to be a GIS program. If you search for this error message over the web, it seems to happen with all sorts of programs as well as customized VB scripts, so it does not seem to be specific to any one application.