Hmmm....I'm not sure that I really encountered any issues that I really need fixed.
The "only" issues that I have had are lack of 64-bit support for our VPN solution at work...but this is the vendors issue and our corporate lack of desire to upgrade our existing infrastructure to support 64-bit...there is nothing that Microsoft can do to resolve this issue. For this reason, since my work laptop has 4GB of RAM, I just went with 32-bit. 3.5GB of RAM is plenty for what I do with this laptop.