Two errors in Event Viewer

Now i had 4 errors: 3 times the Event 3006 LoadPerf, and the second one, but this time it was winlogon.exe

Windows detected your registry file is still in use by other applications or services. The file will be unloaded now. The applications or services that hold your registry file may not function properly afterwards.

DETAIL -
1 user registry handles leaked from \Registry\User\S-...:
Process 640 (\Device\HarddiskVolume1\Windows\System32\winlogon.exe) has opened key \REGISTRY\USER\S-...

usasma said:

Just before shutting down, manually kill anything that's open and kill anything that's running in the System Tray (the Notification Area by the clock).

Then shut down and see if it generates the error again.

The problem is that i do this every time i shutdown(no open windows/apps).
And i dont have many app in my Notification Area(only these which are not closable from there):
Attachment 72752

Code:

Windows detected your registry file is still in use by other applications or services. The file will be unloaded now. The applications or services that hold your registry file may not function properly afterwards.  

 DETAIL - 
 1 user registry handles leaked from \Registry\User\S-xxx:
Process 3232 (\Device\HarddiskVolume1\Windows\System32\msiexec.exe) has opened key \REGISTRY\USER\S-xxx\Software\Microsoft\Windows\CurrentVersion\Explorer\FileExts

Now its msiexec.exe...