User registry handles leaked when shutting down Win 7 Ultimate

I have over 630 events logged in less than a year on my Win 7 Ultimate (64bit) which is basically turned one and off twice per day, all stating that my registry is leaking. Each shut down produces a 1530 event message like this below...

Windows detected your registry file is still in use by other applications or services. The file will be unloaded now. The applications or services that hold your registry file may not function properly afterwards.

Which is then followed by the number of leaks (from 3 to 45) but all relate to REGISTRY\USER\S-1-5-21-2504074074-2207754458-538734185-1000. When I seach for this reference on the C:\ drive it returns me three Roaming folders under App Data. There is only one user on this machine (excluding the administrator). If there is a guest user, it doesn't show up - it boots right to my desktop.

Question - can I somehow turn off this roaming?
I am not storing any destop or user profile on a network, why is this roaming thing needed?

I do not know where to find user profiles, I can only find user accounts in the control panel.

Neutron16 said:

No, one cannot turn this "roaming", because it is part of the system. That folder used to be Documents and Settings\$USER$\Application Data in Windows XP.

Some application causing this problem. More info is required. Screenshots would also be appreciated.

Not sure what sceen shots I should post. The devices that are leaking vary by description and the quantity of entries. It occurs at shutdown - know this by marking down the time I hit the shut down button and then reboot and look at the event viewer. Maybe this means nothing as it is only a warning and nothing else seems to have a problem.