Wacom Cintiq losing signal

I am running Windows 7 with dual monitors, one of which is a wacom
cintiq.
Both monitors started randomly losing signal. The tower was still
running and I could still hear what I had been listening to on
headphones. I forced restart and things returned to normal, but the
problem happened again every hour or so.

This happened five or six times, then on one of the restarts the
computer would not respond to any click I made with the pen or mouse.
It would track the pen/mouse but as soon as I clicked anything (file,
folder, start button etc.) it would freeze and show me the waiting
symbol. Sometimes the waiting symbol would eventually stop but without
performing the action I had attempted. Re-clicking got the same
results.

The clicks would work normally when I started in "Safe mode".

I turned off the power for a day and now when I try to start up the
tower makes a much louder hum than before and the monitors never pick
up the signal.

Any of this sound familiar? I would really appreciate some advice
before having to take it in somewhere.
Thanks.

Thanks,
Both the graphic card and the motherboard are almost three years old.
I don't have an integrated graphics card.
It has been "dusted" pretty recently, but I am going to open it up and clean it out again to see if there is any difference.

JGallant said:

I am running Windows 7 with dual monitors, one of which is a wacom
cintiq.
Both monitors started randomly losing signal. The tower was still
running and I could still hear what I had been listening to on
headphones. I forced restart and things returned to normal, but the
problem happened again every hour or so.

This happened five or six times, then on one of the restarts the
computer would not respond to any click I made with the pen or mouse.
It would track the pen/mouse but as soon as I clicked anything (file,
folder, start button etc.) it would freeze and show me the waiting
symbol. Sometimes the waiting symbol would eventually stop but without
performing the action I had attempted. Re-clicking got the same
results.

The clicks would work normally when I started in "Safe mode".

I turned off the power for a day and now when I try to start up the
tower makes a much louder hum than before and the monitors never pick
up the signal.

Any of this sound familiar? I would really appreciate some advice
before having to take it in somewhere.
Thanks.

Please write down your pc specs (CPU, motherboard, RAM, graphics card,...) and the monitors' model.

XMS3 Dual channel processor (8GB)
Motherboard: Asus P8P67
Graphics card: Asus v621

Oh, and the first monitor is a wacom cintiq 21ux, the second is an AG neovo f-417

JGallant said:

XMS3 Dual channel processor (8GB)
Motherboard: Asus P8P67
Graphics card: Asus v621

Please install Speccy and pick up your correct system specs :)
Speccy - System Information - Free Download