Any drawbacks from using exFAT?

Hi everyone,
I work with a significantly large amount of files which I store in a 2GB flash drive, and, today, I came across an issue of the FAT format, which is that you can't have more than 161 files/folders in a directory.
As the exFAT format is newer, I thought about changing to that one since it will suit my needs.

Now this is my noob question, is there any disadvantage in using exFAT relatively to FAT in my flash drive?

Thanks in advance,
Pedro.

Take a read of this:
exFAT - Wikipedia, the free encyclopedia

The FAT32 file system is limited to 512 file entries in the root of the drive. But as long file names will require 2 or more file entries the actual number of files may be substantially less. There is no limit on the number of files in a subdirectory.

A problem with exFAT is compatibility with other operating systems. It requires Vista or later, XP with an added driver. It is also supported by some later versions of Mac OSX.

LMiller7 said:

The FAT32 file system is limited to 512 file entries in the root of the drive. But as long file names will require 2 or more file entries the actual number of files may be substantially less. There is no limit on the number of files in a subdirectory.

A problem with exFAT is compatibility with other operating systems. It requires Vista or later, XP with an added driver. It is also supported by some later versions of Mac OSX.

My flash drive is formatted on FAT, not FAT32. And 512 entries on the root still seems little, however a lot more than what I have right now.
I read exFAT will lose data if you remove the drive when it is writing, though, which seems to be a drawback