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If you don't have a permanent scan antivirus, download Combofix ComboFix Download
If you're not sure your antivirus/antimalware is "alive" all the time, disable them temporarily before running Combofix. This is very important since if your antivirus is up and running and you run Combofix you may damage your computer. Anyway, Combofix will tell you what programs you must shut down.
Running Combofix will clean all malware and would be of great help if your problems are caused by malware.