How to remove popup box inside browser

pcwin

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I keep getting a popup at all my browsers (firefox, internet explorer, chrome) at random times.

The popup displayed this message: sin1.g.adnxs.com say: You won an iphone (screenshot http://i.imgur.com/at344LM.png )
I have clicked x but it still popups after some time.
I have clicked cancel but it still popups after some time.

I have followed these steps at Remove ib.Adnxs.com pop-up virus (Removal Guide) but the popup still happens.

How can I remove the popup?

I have spent lots of time but I still could not get rid of the popup.

Thanks a lot.
 

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Windows 7 Home Premium 64 Bit
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Intel
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ASUS P7P55DE-PRO
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WD Black
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MSE

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PC/Desktop
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Windows 10 Pro X64
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