Virus, Windows update, user profile and now Genuine Windows problem

A sorry story - I went to download a copy of Opera, and must have gone to a non-genuine site because all of a sudden I got a host of pop-ups, inc one telling me about a wonderful "Optimiser" product. Had a go at cleaning the virus and then performed a windows update that had come along.
Next boot i have lost my user profile..

Long story short, I think I have cleaned the virus, fixed the user profile issue, but now am lost in the non-genuine Windows nightmare. Diagnostic report below.

Code:

Diagnostic Report (1.9.0027.0):
-----------------------------------------
Windows Validation Data-->

Validation Code: 50
Cached Online Validation Code: N/A, hr = 0x80070005
Windows Product Key: *****-*****-YYFRF-BT3R9-GVFPD
Windows Product Key Hash: 1H2ceMu35VtLDL83p6D/Az8t6k4=
Windows Product ID: 00426-104-2695677-85957
Windows Product ID Type: 5
Windows License Type: Retail
Windows OS version: 6.1.7601.2.00010100.1.0.001
ID: {17D736EA-ED14-4184-8789-CE8BE0BC3661}(3)
Is Admin: Yes
TestCab: 0x0
LegitcheckControl ActiveX: N/A, hr = 0x80070002
Signed By: N/A, hr = 0x80070002
Product Name: Windows 7 Ultimate
Architecture: 0x00000009
Build lab: 7601.win7sp1_gdr.140706-1506
TTS Error: 
Validation Diagnostic: 
Resolution Status: N/A

Vista WgaER Data-->
ThreatID(s): N/A, hr = 0x80070002
Version: N/A, hr = 0x80070002

Windows XP Notifications Data-->
Cached Result: N/A, hr = 0x80070002
File Exists: No
Version: N/A, hr = 0x80070002
WgaTray.exe Signed By: N/A, hr = 0x80070002
WgaLogon.dll Signed By: N/A, hr = 0x80070002

OGA Notifications Data-->
Cached Result: N/A, hr = 0x80070002
Version: N/A, hr = 0x80070002
OGAExec.exe Signed By: N/A, hr = 0x80070002
OGAAddin.dll Signed By: N/A, hr = 0x80070002

OGA Data-->
Office Status: 109 N/A
OGA Version: N/A, 0x80070002
Signed By: N/A, hr = 0x80070002
Office Diagnostics: 025D1FF3-364-80041010_025D1FF3-229-80041010_025D1FF3-230-1_025D1FF3-517-80040154_025D1FF3-237-80040154_025D1FF3-238-2_025D1FF3-244-80070002_025D1FF3-258-3

Browser Data-->
Proxy settings: N/A
User Agent: Mozilla/4.0 (compatible; MSIE 8.0; Win32)
Default Browser: C:\Program Files (x86)\Mozilla Firefox\firefox.exe
Download signed ActiveX controls: Prompt
Download unsigned ActiveX controls: Disabled
Run ActiveX controls and plug-ins: Allowed
Initialize and script ActiveX controls not marked as safe: Disabled
Allow scripting of Internet Explorer Webbrowser control: Disabled
Active scripting: Allowed
Script ActiveX controls marked as safe for scripting: Allowed

File Scan Data-->

Other data-->
Office Details: <GenuineResults><MachineData><UGUID>{17D736EA-ED14-4184-8789-CE8BE0BC3661}</UGUID><Version>1.9.0027.0</Version><OS>6.1.7601.2.00010100.1.0.001</OS><Architecture>x64</Architecture><PKey>*****-*****-*****-*****-GVFPD</PKey><PID>00426-104-2695677-85957</PID><PIDType>5</PIDType><SID>S-1-5-21-3973918536-1164609290-4048156035</SID><SYSTEM><Manufacturer>System manufacturer</Manufacturer><Model>System Product Name</Model></SYSTEM><BIOS><Manufacturer>American Megatrends Inc.</Manufacturer><Version>4801</Version><SMBIOSVersion major="2" minor="7"/><Date>20140725000000.000000+000</Date></BIOS><HWID>54553107018400F2</HWID><UserLCID>0809</UserLCID><SystemLCID>0409</SystemLCID><TimeZone>GMT Standard Time(GMT+00:00)</TimeZone><iJoin>0</iJoin><SBID><stat>3</stat><msppid></msppid><name></name><model></model></SBID><OEM/><GANotification/></MachineData><Software><Office><Result>109</Result><Products/><Applications/></Office></Software></GenuineResults>  

Spsys.log Content: 0x80070002

Licensing Data-->
On a computer running Microsoft Windows non-core edition, run 'slui.exe 0x2a 0x46' to display the error text.
Error: 0x46 

Windows Activation Technologies-->
HrOffline: 0x00000000
HrOnline: N/A
HealthStatus: 0x0000000000000000
Event Time Stamp: N/A
ActiveX: Registered, Version: 7.1.7600.16395
Admin Service: Registered, Version: 7.1.7600.16395
HealthStatus Bitmask Output:


HWID Data-->
HWID Hash Current: NAAAAAEAAwABAAEAAQACAAAAAgABAAEAhFFMpc7/dMQmtWTHDtqAzzC6ipvkrrKaqIc0IQ==

OEM Activation 1.0 Data-->
N/A

OEM Activation 2.0 Data-->
BIOS valid for OA 2.0: yes, but no SLIC table
Windows marker version: N/A
OEMID and OEMTableID Consistent: N/A
BIOS Information: 
  ACPI Table Name    OEMID Value    OEMTableID Value
  APIC            ALASKA        A M I
  FACP            ALASKA        A M I
  HPET            ALASKA        A M I
  MCFG            ALASKA        OEMMCFG.
  FPDT            ALASKA        A M I
  DMAR            A M I         OEMDMAR
  SSDT            INTEL        CpuPm

I have attempted the commands provided elsewhere regarding sppsvc, which were successful. But I can't activate Windows because I can't get an activate link.

If I type "SLUI 4" into the run command it fails with a message 0x80070005 "Access is denied".