Hi:
It's up to the user, of course.
And each computer is unique.
FWIW, compacting folders (an important feature, to be sure) is already handled by TB by default (with options to customize those settings, if desired) and can be done manually from within TB, as well.
There is no need to use a 3rd-party app for this.
If you do opt to use the CCleaner options for Fx or TB, I suggest backing up your profile before running it, just in case. YMMV, but there is a long history of CCleaner mucking up both Fx and TB.
>>>Your choice, of course.<<<
MM