Fails to boot

ronnielee09

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My computer will lock up at will. When I re-boot I get the message that no ndlr is found. The BIOS does not recognize the hard drive. When I plug the SATA cable into another socket, the BIOS will recognize the HD. I then have to click F8 to reset the boot order. Is this a bad motherboard, Hard Drive, or something in the OS? I have Win 7 Home Premium, Asus M3At8 motherboard, Radeon HD3200 video card, 4GB of Ram. I have changed SATA cables and it did not help. Thanks for any tips you can give me. This is about to drive me nuts!
 

My Computer

Computer type
PC/Desktop
Computer Manufacturer/Model Number
Custom
OS
windows 7 Home Premium 32 bit
CPU
AMD 3.10
Motherboard
ASUS M3A78-EM Rev X.0x
Memory
4 GB
Graphics Card(s)
NVIDA GForce 220
Sound Card
Built In on Motherboard
Browser
Firefox
did you install the O/S with a a main drive and a secondary drive ?
 

My Computer

Computer Manufacturer/Model Number
MSI
OS
Ultimate 7
CPU
1055T @ 3.7
Motherboard
MSI
Memory
16g Corsair
Graphics Card(s)
HD5770
Sound Card
Onboard
Monitor(s) Displays
FLat 23
Hard Drives
SSD 64g Kingston
500 Gig Western
PSU
850 Thermaltake
Yes, I upgraded from Win XP. I have disconnected the second internal SATA drive, but still have my external USB drive hooked up. Disconnecting the internal drive did not help. I do have my primary HD partitioned in a dual boot with XP. I really don't need XP. I could delete this partition if you think it would help.
 

My Computer

Computer type
PC/Desktop
Computer Manufacturer/Model Number
Custom
OS
windows 7 Home Premium 32 bit
CPU
AMD 3.10
Motherboard
ASUS M3A78-EM Rev X.0x
Memory
4 GB
Graphics Card(s)
NVIDA GForce 220
Sound Card
Built In on Motherboard
Browser
Firefox
I asked only because sometimes windows will place needed boot files on the secondary drive which causes a mess for boot issues , I have always installed a fresh install in any rig with a single drive at first and then added secondary drives after the install.
 

My Computer

Computer Manufacturer/Model Number
MSI
OS
Ultimate 7
CPU
1055T @ 3.7
Motherboard
MSI
Memory
16g Corsair
Graphics Card(s)
HD5770
Sound Card
Onboard
Monitor(s) Displays
FLat 23
Hard Drives
SSD 64g Kingston
500 Gig Western
PSU
850 Thermaltake
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