GTA IV is more based on the cpu than gpu. I haven't tried the 220 but looking over its specs its not a horrible card. Not earth moving or top of the line, but also not horrible
For testing purposes I ran a ATI 2600XT AGP with GTA IV and it actually played it.. The overclocked P4 though, struggled very bad. (obviously)
Needless to say though running at high/very high settings still needs a good card so its good to see the 220 can acomplish that.