I don't believe it's possible. High contrast is a system theme. It's possible to have windows switch to a basic theme when running certain programs, but even that reverts the whole system. A Guy
My Computer
At a glance
Windows 10 Home x64INTEL Core i5-750 Quad-Core 3.37GHzHyperX Fury Black Series 8GB (2 x 4GB) 1866MhzEVGA GeForce GTX 750 Superclocked 1GB 128-Bit...
I was hoping for a solution :/ the 2013 suite of office is blindly bright and that "dark grey" option is an utter joke. High contrast is the only way to make it bearable in the wee hours of the morning