Well, McAfee failed to quarantine and remove an Autoloader Trojan from my system just an hour ago, so what does that tell you? I wouldn't use McAfee if you didn't have to (I'm only using it because it's free for a while and saves me the burden of dropping a few bucks I really can't afford right now on better software).
And interestingly, the last time I ever used McAfee, when I uninstalled it from our old XP Desktop, I immediately got slammed with dozens of nasties - pretty sure that was by their design, too in order to make it appear as "see what happens without us?!" kind of a thing - trying to scam us all back into it in other words. So again, I really would steer clear of it if you can.
Personally, I'm a fan of Nod32... I used it for two years and never once had a single problem, or major melt-down of my system. I almost thought it too good to be true because it was working so well, I thought it might not be working at all (if that makes any sense to you), but nope, it was the real-deal. But, it's a little steep for me and so that's why I don't have it again on this system - yet.