While some might believe that BitLocker is more suited in a corporate business environment, I do not believe this to be the case. Even in a home environments, full disk encryption is a good idea.
Latops and USB drives are not the only thing that can be stolen. Just because you have a hard-to-move desktop doesn't mean that it cannot be stolen. Protecting personal information such as online banking information, emails, etc. is just as important as any financial records of a business.
All my drives are BitLocker encrypted, both fixed, external and flashdrives (using BitLocker To Go). I only kepp one USB flash drive unencrypted, but that's only because I use it for work, and I often encounter XP machines that cannot read BitLocker-to-Go encrypted USB drives.
What can I say, really. I'm a born paranoid, and I don't want anybody getting their grubby little paws on anything that belongs to me, unless I give it to them.