Let me see here.... this is my own personal experience. My copy of Windows 7 Home Premium is 64-bit and was pre-installed on this PC
works fine:
Duke Nukem Manhattan Project
Return To Castle Wolfenstein
Star Trek Elite Force II
Plants Vs Zombies
Half-Life 2
Portal
Garry's Mod 11
Postal 2
Ys The Oath In Felghana
Serious Sam 2
Doom 3
Call of Cthulhu: Dark Corners of the Earth
Halo
Cave Story Deluxe
BSNES- high-requirement SNES emulator
Minor issues. Might be due to Aero incompatibility but shutting it off doesn't seem to help. Could be my monitor or onboard graphics as well. Issues are color depth, text, etc.:
Neighbours From Hell
Neighbours From Hell 2
MapleStory
Plantasia
Westward- unplayable in full screen mode thanks to the text being mangled. Fine in windowed mode
Problem games-
The Simpsons Hit & Run - load times make it unplayable. Literally seems to want to take 10 minutes to load a level. I do not believe this is a problem specific to Windows 7.
Max Payne- will NOT install due to a 16-bit installer
Blood 2- will NOT install due to a 16-bit installer
Ys VI Ark of Napishtim- installs fine. Will NOT load nor will the game patches work, therefore I can't even install the english translation patch. Applocale was needed to run this game in Windows XP, but that doesn't seem to work in Windows 7.
Not fully tested. I have booted the game to the menu and everything seems fine so far, but I have not had time to play them yet:
Serious Sam First Encounter
Serious Sam Second Encounter
Shadow Man
Oni
Kiss Psycho Circus: The Nightmare Child