If you are trying to save in any of the protected system folders, as I suspect is your case as most of the INI files are stored in C:\Windows or its subfolders, the easiest way is to run Notepad as administrator and open the INI file in question from Notepad's File > Open menu. As Notepad runs now with built-in administrator rights, you can save to any location.
Alternatively you can save the file on Desktop, then copy & paste it to a system folder. Access will be denied even now, with a small difference: the system allows you to select and use built-in administrator rights to save the file. To do this simply click Continue:
Kari
My Computer
At a glance
Windows 10 Pro x64 EN-GB1.6 GHz Intel Core i7-720QM Processor6 GBATI Mobility Radeon HD 5850 Graphics
Computer type
Laptop
Computer Manufacturer/Model Number
HP ENVY 17-1150eg
OS
Windows 10 Pro x64 EN-GB
CPU
1.6 GHz Intel Core i7-720QM Processor
Memory
6 GB
Graphics Card(s)
ATI Mobility Radeon HD 5850 Graphics
Sound Card
Beats sound system with integrated subwoofer
Monitor(s) Displays
17" laptop display, 22" LED and 32" Full HD TV through HDMI
Screen Resolution
1600*900 (1), 1920*1080 (2&3)
Hard Drives
Internal: 2 x 500 GB SATA Hard Disk Drive 7200 rpm
External: 2TB for backups, 3TB USB3 network drive for media
Cooling
As Envy runs a bit warm, I have it on a Cooler Master pad
