The folder in your original post has 32 random characters. MSE creates temp folders with 32 random characters too - but only when certain parts of MSE require updates (scanning engines vs. definitions). You did not see another temp folder because MSE did not need to make one today.
The folder should go away after the update(s) completes. Perhaps something has changed recently that is causing some of them to be left behind. Maybe the change was on Microsoft's side or maybe Malwarebytes has changed and is preventing the rapid creation & deletion of certain folders. Maybe those that use MSE & MBAM could let us know if they see these folders too. Even the automatic updates can create these folders. I've seen computers with 3 or 4 of these folders. I just delete them.
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I deleted the existing folder to find out if another would be created my the MSE update, but no new folder appeared.
While it does not hurt to delete them, they do not get reused. A new one (with a different name) will be created the next time one is needed.
If you want to see one of these folders, use Internet Explorer to download and run one or two of MSE's manual update files. Visit this webpage:
https://www.microsoft.com/security/portal/definitions/adl.aspx
Scroll to the bottom section named "
Network Inspection System updates".
See the image in step two.
Take note of all of the version info on that "About" screen.
Scroll back up to the section named "
Manually download the latest updates".
Click on the applicable link to download the manual update file. (~150MB)
Select
Run. Do not select
Save.....
That makes the file download to and run from IE's Temporary Internet Files (TIF) folder. Running from there should cause the installer to create one of these temp folders. The installer might create a temp folder no matter where it is run from. I'm just guessing that running from the TIF folder gives you the best shot at seeing a random folder being created. That said, if no updates are required, the temp folder might be create and deleted too fast for you to see via Windows Explorer. You might need to run
Process Monitor to capture the sub-second even.
The manual update file does not make any screens for you to see or interact with. It is kind of hard to know when it has finished. If updates are applied, it may animate MSE's icon in the system tray (notification area). [I do not use MSE and I cannot test MSE inside a virtual machine right now. So all of this is from memory.] After you run that manual update file, check the "About" screen again to see if any of the numbers have changed.
Also, you might want to download/run the manual update file for the
Network Inspection System. I'm not sure if the NIS updates are a part of the larger file that you just downloaded above. You tell us
