When those items are grayed out that means the permissions are being inherited from the parent folder. This is a normal and common situation. To change the permissions you would need to first remove the inheritance. Normally there is no need to do this.
Creating a User Defined Service in Windows 7
But it is a little bit wrong
-> under HKEY_LOCAL_MACHINE\SYSTEM\CurrentControlSet\Services\MyService: create a 'Parameters' key
-> under the above key, create an 'Application' value of type REG_SZ and specify there the full path of your app executable (including the extension). For example: Application: REG_SZ: D:\TOOLS\VI.EXE
-> OPTIONAL: under the above key, create an 'AppParameters' value of type REG_SZ and specify the parameters for your app. For Example:
AppParameters: REG_SZ: C:\TMP\FOO
-> OPTIONAL: under the above key, create an 'AppDirectory' value of type REG_SZ and specify the current directory to use for the app, eg:
AppDirectory: REG_SZ: C:\TMP