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Synaptics Touchpad - Auto disable with USB mouse
No option to disable your Synaptics Touchpad when you plugin a USB mouse? The function is there but is disabled in the registry. Click the link and scroll down to message #9. Make the change, reboot and the auto disable works immediately if you have a USB mouse plugged in. Making the change in HKLM didn't work for me but HKCU did the trick. Navigate to the Synaptics settings page and the option to disable is now there. No credit due here, just passing it on to help others.
NP8662 - Auto-deactivate touchpad (scroll down to message #9)