Many software uses it. https://en.wikipedia.org/wiki/.NET_Framework you prob have 3.5 and 4.0-4.5 on your system at the moment, they are different do not remove one and leave the other you want both. Hope this answers your question.
It looks like some updates failed on the first attempt, and then succeeded on the next attempt, such as KB3127220.
When you check for updates now, do you get any updates offered ?
If they aren't re-offered, i think you are ok.
Gyration wireless, Logitech wireless, Dell USB wired
Mouse
Gyration wireless, Logitech wireless, V7 USB wired
Internet Speed
Spectrum - 100Mbps D / 10Mbps U
Antivirus
Avast, MBAM3, EMET, WinPatrol
Browser
Pale Moon, Firefox, IE
Other Info
2 multi-boot PC's
Mainly HTPC/Office/Gen purpose (no gaming).
Trendnet USB KVM.
LG DVD burner/Blue Ray Player.
Tray system for removable SATA backup drives.
Not currently OCd, under-volted.
I use Hybrid sleep, rarely re-boot or shutdown.
Hauppauge HD-PVR, Avermedia PCIe TV Tuner, Hauppauge PCI TV Tuner.