If it's my own install, I enable hidden Administrator account first, login again, then delete named User account in User Accts, turning UAC down to lowest setting. Now I am the one and only Admin.
I customize the start menu so Computer, Control Panel fold out a menu for easier access, show Run, Video and Downloads folder.
Install MSE or Avast, check Windows Update to get them started, especially looking for optional newer driver Updates. Check Device Mgr. Adjust screen res and up DPI to 120% for better readability.
Then I install Works, flash, Reader, Java, CCleaner, Auslogics defraggers from stick.
Then the dazzle: copy from stick
collection of 120 Win7 national edition backgrounds into Pictures, rightclick desktop to Personalize them as desktop slideshow. These are the most lavish pictures ever taken and provide a thrill every time. Next I place weather, CPU and calendar gadgets, drag Word processor, SnipTool, Calc, IE8 to taskbar for quicker access and rightclick history.
In IE8 (which is finally perfect) I choose all the Google accelerators for rightclick define, map, translate, search, map genomes, etc; Compatibility updates, import favorites.
I then go into MSconfig and turn off all Startup items except AV, StikyNotes, and gadgets. This keeps startup under 30 seconds.
Finally I clean it up with CCleaner "Run Cleaner" and Registry tab, then defrag with Auslogics Disk and Registry defraggers.
It takes an hour. Everything else is added as needed.