Thanks for your replies.
DeaconFrost, You install all your programs on the system drive because you have plenty of room. You install your games on the second drive because they are big. You don't say - do you know of a problem with installing programs on the second drive?
wanchoo, You say you tried both options. What was the problem with installing programs on the second drive?
huffman said he has seen no difference between the two. Maybe that's what I want to hear, because I don't like loading up the system SSD to capacity.
Any other comments? Thanks!