I would not recommend the Naga if you have large hands, the back 6 buttons will be largely useless to you. The Naga is designed strictly for MMOs with a large number of abilities.
Razer Naga - MMO Gaming Mouse | Razer Online Store
If you do go for an original Naga,
it would be wise to stay very far away from the Naga Epic. This mouse is a sad excuse for the original Naga.
The Naga Hex is designed more for MOBA and FPS games, it has 8 buttons arranged in a hex rather than 12. I've had a chance to play with one of these for a week, it is perfect IMO for these types of games.
Razer Naga Hex - Expert MOBA/Action-RPG Gaming Mouse - Razer™ | For Gamers. By Gamers.™
I do not have any experience with the Logitech you mentioned.
As far as optical vs laser, I think it really comes down to a personal preference. I've owned Razer products for a while, and most are laser.
I am not affiliated with Razer in any way, just an enthusiastic user of their products.