Unable to uninstall updates impacting other programs,Windows 7

[westway]

There are two Microsoft updates that has caused a very important program to stop working. I have identified the two that caused the problem, however they cannot be removed per the Microsoft message that once installed they cannot be removed. Please, is there another way I can remove them so I can get my program up and running?

 

[NoelDP]

It would help if you told us
1) the affected application
2) the KB numbers of the problem updates