I have tried all those options. I can use all my Mac drives, irrespective of format, on my older XP PC with MacDrive9. I think the problem is within the Windows 7 PC. I have updated the USB controllers, etc. from Gigabyte website using their Download Center Tool, but the problem persists. I have tried two identical Seagate Expansion 2TB USB 3 drives with no success. Both of them work perfectly on XP, and check out on Mac in Disk Utility as being troublefree. They contain a large archive of files, including MP3, DVD & CD disk images (.cdr & .toast), books in .pdf format, disc labels (.psd) and inserts (Word). Also tried three other portable drives, one with HFSJ format, another with HFS+. Both of those work. When I format a portable drive with Mac OS extended, the drive does not open, and is listed in Device Manager as having no driver (code 28), the same as the two Seagate drives. I have tried uninstalling MacDrive and reinstalling it. Can you suggest what else I might try? I believe this failure has only begun in the last couple of weeks.