Sorry Tweek, but I categorically disagree. NOD32 has had this problem for a very long time (several years) and they have not yet fixed it.
Yes, it does degrade system functionality.
how do I know this?
Because when a place I worked for, we stopped selling Norton due to many reason, main one was they wantesd to charge us about 80$ to help them fix their definition files to clean a system that Norton would not clean. We looked for alterntives and at the time, NOD32 was the best offer we got, and it was very stable and didn't have these problems. Then they did a full upgrade and changed the GUI and this very problem began. This was at least 2 or 3 years ago. We worked with ESET quite a bit on this and on their Server Solutions with other issues. The support was ok, they did try to help as much as possible, but started blaming Windows for the issue. We did continue to sell it as it was not an issue on every system. But still, more often than we liked. We began looking for alternatives and Live OneCare came along, we immediately started testing it heavily and switched to it exclusively after that. At the time, Live OneCare did a pretty darn good job of keeping systems clean, not so good at cleaning an infected system. We kept tabs on this in many ways, through fairly decent testing of our own. I had a system once with over 5000 infections, literally, and no, they were not cookies. I saved them to a CD ROM and used it for testing, Not sure if I still have it though.
Incidentally, nothing could clean this system completely, So we did have to reload it, But, it also had AVG installed on it, and running the full scan, found very few of them, and refused to clean any of it. A main reason AVG is garbage.
Suffice to say, Eset is a good product when it works, but, it is flakey and has been, they refuse to fix the issue.
MSE may not be the absolute best product on the market, but it is quite adequate for those who surf safely.