Yup, I avoid games with GameGuard or any sort of frustrating root-kit like behavior from an anti-cheat and copy protection package. You'll see most developers from China, Korea, Japan, etc. use these since that sort of behavior is rampant there.
It's a shame. I tried Rappelz once, and it's a good engine and MMO-style game for free, but was put off by the horrible 'Engrish' and poor quests/story-line. On that other hand, Phantasy Star Online/Universe was much better (not free), but still riddled with this bad GameGuard-like software.
That stuff is trouble, and even when you uninstall your game, that crap is still left behind.